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THE ORIGINATOR OF POPULATION‑SCALE BEHAVIORAL STRESS MEASUREMENT ARCHITECTURE

The Future of Behavioral Health Has a Number.

A pre‑diagnostic behavioral health measurement designed for early, repeatable assessment at population scale.

Built on a measurement architecture first published in a 2009 international patent filing and clinically validated through peer‑reviewed research conducted in collaboration with Mayo Clinic.

You can’t manage what you don’t measure.
This is the measurement infrastructure the industry has been missing.

93% of Covered Lives Are Invisible
→ See Why Learn How It Works
What This Is

Six Things To Know

01
Category Originator
Not a participant. Not a competitor. The originator.
First patent filing: 2008. First international publication: 2009. The category didn't exist before this.
02
Infrastructure Metric
Not a program. Not a tool. Not an app.
Stress Number™ is a measurement standard — like FICO, A1C, or HEDIS.
03
Clinically Validated
Mayo Clinic collaboration. Peer-reviewed publication. EHR-ready.
This is the level of proof that health systems and payers require.
04
Intellectual Property Strategy
Multi-family patent architecture spanning six system layers, building on foundational published prior art from an international patent publication in 2009.
Additional filings are being prepared to extend protection across next-generation system capabilities.
05
Measurement Gap
Behavioral health is the only major clinical domain without a standardized measurement layer.
The Stress Number™ is designed to fill that gap. Unmeasured behavioral risk creates $5M+ in annual exposure per 10,000 covered lives.
06
Controlled Access
Institutional Access is reviewed individually.
A single Strategic Foundational Partner seat is currently under consideration.
Category Firsts

Before There Were Platforms, Programs, or Categories

Stress Number™ established the foundation — first filed in 2008, published globally in 2009.

01
First Category-Originating Prior Art
Foundational measurement architecture publicly disclosed in international patent filings (2008–2009), predating the digital behavioral health category.
02
First Pre-Diagnostic Behavioral Health Biomarker
A pre-diagnostic behavioral health signal designed for early, repeatable measurement — before crisis, before diagnosis.
03
First Clinically Validated Multi-Domain Metric
Validated across home, work, and social domains through peer-reviewed research in collaboration with Mayo Clinic.
04
First Behavioral Health Metric Built as Infrastructure
Designed as a measurement standard — not an application, not a therapy, not a program.
05
First Biomarker Designed for Population Scale
Engineered for longitudinal, population-level measurement across clinical, employer, payer, and public health systems.
06
First Metric to Unify Stress, Anxiety, and Depression
A single normalized score capturing overlapping behavioral health risk without diagnostic labeling.

40+ category-first positions and architecture claims — available through Institutional Access.

The Problem

What’s Broken in Behavioral Health

Unmeasured Stress Is Healthcare’s Most Expensive Blindspot

Behavioral health is the only major clinical domain without a standardized measurement layer.

Clinicians face a fragmented landscape of screening tools that don’t talk to each other. PHQ-9, GAD-7, PSS-10—each measures something different, on different scales, with different thresholds. There is no pre-diagnostic signal that works across conditions or systems.

Organizations face a behavioral health crisis they can’t quantify. Without a common metric, employers, health systems, and payers are forced to react to claims data rather than intervene early.

What’s missing is a pre-diagnostic measurement standard.

The Solution

One Number.
Three Domains.
Clinically Validated.

Stress Number™ is a clinically validated metric that measures stress, anxiety, and depression risk across three life domains: Home, Work, and Social.

Unlike single-dimension tools, Stress Number™ captures context.

It delivers a 0–30 score, validated by Mayo Clinic, with a clinical threshold of ≤23 identifying elevated risk.

It is:

  • Easy to administer (3 minutes)
  • Clinically meaningful
  • Comparable across populations
  • Actionable

One number. Three domains. Clinical precision.

Stress Number™

Standardized Behavioral Health Risk Measurement

The Stress Number™ is a clinically validated measurement designed to quantify behavioral health risk across three life domains: home, work, and social environments.

The Stress Number™ represents the first clinically validated behavioral health biomarker — a standardized measurement that quantifies stress, anxiety, and depression risk across home, work, and social domains. Validated through peer-reviewed research and developed in collaboration with Mayo Clinic, it functions as a consistent measurement layer across clinical, employer, payer, and population health systems.

This marks a turning point: The Oxygen Plan™ is transitioning from experimental assessment tools toward infrastructure-grade measurement that supports decisions, stratification, and outcomes at scale.

How Measurement Standards Work
Standard Characteristic A1c (Diabetes) Stress Number™ (Behavioral Health) Current Behavioral Health Practice
Single standardized metric ✓ One number (glycated hemoglobin %) ✓ One number (0–30 score across three domains) ✗ Multiple fragmented tools, no shared metric
Longitudinal tracking ✓ Tracks change over time (quarterly) ✓ Tracks change over time (configurable intervals) ✗ Point-in-time snapshots, no consistent longitudinal record
Cross-setting comparability ✓ Same metric across primary care, specialty, payer, public health ✓ Same metric across clinical, employer, payer, population settings ✗ Different tools in different settings, no comparability
Population stratification ✓ Risk tiers drive care pathways and resource allocation ✓ Validated cutoff (≤23) enables risk stratification at scale ✗ Subjective assessment, inconsistent thresholds
Reimbursement alignment ✓ Embedded in billing codes and quality measures ✓ CPT billing pathway compatible ✗ Limited reimbursement pathways
Non-diagnostic signal ✓ Pre-diagnostic indicator ✓ Pre-diagnostic signal for behavioral risk ✗ Often conflated with diagnosis
Governance and stewardship ✓ Governed by standards bodies ✓ Governed by The Oxygen Plan Corporation ✗ No unified governance
‹ Swipe to see all columns ›
See clinical validation
Clinical Validation

Built With Clinical Rigor

Stress Number™ was developed in collaboration with Mayo Clinic and validated through peer-reviewed research conducted by Mayo Clinic research personnel.

The research demonstrated ROC AUC performance of 0.88–0.92 against established clinical instruments (PHQ-9, GAD-7, PSS-10), with a validated cutoff threshold (≤23) identifying elevated risk.

Stress Number™ functions as a longitudinal measurement standard for behavioral health — analogous to how A1C functions in diabetes management — enabling consistent risk assessment across clinical, employer, payer, and population settings.

Results were published in a peer-reviewed journal—not a white paper, not a press release. This is the level of validation that health systems, payers, and regulators require before adopting a new measurement standard.

This is not a wellness estimate. It is a pre-diagnostic signal with clinical evidence.

Clinical Validation — Clinically validated through peer-reviewed research published in Archives of Psychology (2018) and conducted in collaboration with Mayo Clinic.

Williams DE, Lucas E, Haugen D, Creagan ET. Initial clinical validation of The Oxygen Plan Stress Number. Archives of Psychology. 2018;2(2).

How It Works

From Input to Insight

The Oxygen Plan™ operates as a measurement and routing layer:

1. User completes assessment

2. Stress Number™ generated across three domains

3. Risk stratification occurs

4. Guided referrals and follow-ups enabled

5. Outcomes tracked longitudinally

The platform integrates cleanly into existing workflows—supporting clinicians without replacing them.

Who It's For

Behavioral health is the only major clinical domain without a standardized measurement layer.

Built for Systems, Not Just Sessions

Stress Number™ serves the organizations responsible for behavioral health at scale.

Health Systems & Hospitals — A standardized behavioral measurement layer for early detection, clinical triage, EHR-aligned workflows, and longitudinal outcome tracking across patient populations.

Employers & Benefits Platforms — Population-level behavioral risk measurement that enables early intervention, workforce resilience strategies, and measurable ROI on mental health investment.

Payers & Managed Care — A standardized behavioral risk signal that supports actuarial modeling, claims-aligned measurement, and evidence-based referral routing within value-based care.

Government & Public Health — CMS is expanding mandatory behavioral health quality reporting across Medicaid, CHIP, and the Adult and Child Core Sets. O2OS™ provides the population-scale measurement infrastructure that supports standardized screening, quality reporting, and CPT-aligned reimbursement across state and federal programs.

Clinical Research & Academic Centers — A validated and replicable measurement framework for behavioral health research, program evaluation, and cross-site outcome comparison.

Diagnostics & Life Sciences — A clinically validated pre-diagnostic behavioral measurement signal (ROC AUC 0.88–0.92) that supports trial stratification, patient monitoring, and real-world evidence generation. Designed for integration into diagnostic platforms and population health workflows at scale.

Population-Scale Structural Exposure
$593M
Net structural exposure per 1,000,000 covered lives.
Medical-only. Parameterized. Auditable.
93% of covered lives sit outside structured behavioral measurement infrastructure.
937,500 of every 1,000,000 are unmeasured, misclassified, or unrouted.
See the Full Exposure Model →
Governance & Ethics

Measured With Care. Governed With Purpose.

Behavioral health data demands restraint.

The Oxygen Plan™ was built with governance, transparency, and ethical use at its core.

Measurement exists to support care—not to manipulate, monetize distress, or replace human judgment.

We believe infrastructure should serve people, not extract from them.

About The Oxygen Plan™

A Clearer Signal Before Crisis

The Stress Number™ measurement framework originates from a 2009 international patent publication — one of the earliest system-level architectures for quantifying behavioral stress across life domains. What is now a clinically validated, institution-ready metric began as a published disclosure that predates the digital behavioral health category itself.

Founded by Eric Lucas — the named inventor on the original filing and a former Fortune 250 VP and Corporate Officer — The Oxygen Plan Corporation has developed this work over 18 years through clinical validation with Mayo Clinic, EHR-ready architecture, and systematic intellectual property development.

The infrastructure has been self-funded and deployed through enterprise and EAP channels, including sustained engagement with Microsoft and a government entity across a workforce exceeding 100,000 employees.

Clean cap table. One institutional investor. Debt-free. 100% infrastructure ownership.

Public record priority — 2009 international patent publication
Independent clinical validation — Mayo Clinic, peer-reviewed, ROC AUC 0.88–0.92
Longitudinal stewardship — 18 years, founder-led, no dilution chaos

This is infrastructure built deliberately for the long term stewardship of the category — not a product rushed to market.

TECHNOLOGY & INTELLECTUAL PROPERTY

Built to Last. Built to Scale.

The foundational measurement architecture underlying O2OS™ was first disclosed publicly in 2009 through an international patent publication, predating the emergence of digital behavioral health as a recognized sector. The named inventor on that original filing, Eric Lucas, has continued to develop the architecture through clinical validation, platform engineering, and systematic intellectual property expansion over 18 years.

Next-generation multi-family architecture in active development, with additional filings being prepared.

The infrastructure is built on:

  • Foundational prior art published globally in 2009, predating the digital behavioral health category.
  • Mayo Clinic clinical validation (peer-reviewed, 2018)
  • Epic EHR integration readiness
  • CPT billing pathway compatibility

This is not a feature set. It is a defensible infrastructure position with a documented lineage that predates the market it serves.

Patent activity is ongoing.

Category Context

The Architecture Predates the Category

The Stress Number™ patent was filed in 2008 — before the App Store launched.

2008–2009
International patent publication discloses system-level architecture for quantifying behavioral stress across life domains.
2010–2012
Consumer mental health apps emerge. No shared measurement standard exists.
2013–2016
Digital wellness platforms scale across employers and payers. Behavioral health remains fragmented, subjective, and non-comparable.
2015–2018
Measurement framework clinically validated through peer-reviewed research in collaboration with Mayo Clinic.
2018–Present
Behavioral health adoption accelerates across health systems, employers, and public health. A standardized measurement layer still does not exist at scale.

Once established, measurement standards tend not to be replaced — they become reference points.

Institutional Access

Structured Access for Qualified Institutions

For qualified institutional inquiries, we provide structured access to foundational documentation including clinical validation, intellectual property timeline, and infrastructure overview. Access is reviewed individually.


A single Strategic Foundational Partner seat is currently under consideration.

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AI-ERA INFRASTRUCTURE

The Missing Input Layer

Every major clinical domain has a standardized input for AI. Behavioral health never did.

AI systems in healthcare can model labs, claims, imaging, and genomics with increasing precision — because each has a standardized, machine-readable input layer: LOINC, ICD, DICOM, CPT, HL7/FHIR.

Behavioral health has not historically had a multi-domain, upstream, longitudinal input layer designed for AI-era prediction. Most current instruments are diagnosis-adjacent and were not designed as structured computational inputs.

The Stress Number™ is designed to serve as that upstream input — a single, clinically validated signal that AI systems can compute on without assuming behavioral validation risk.

Infrastructure doesn't compete. It embeds.

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If you are exploring better ways to measure, understand, or support behavioral health at scale, we welcome the conversation.